King George's Medical University, Lucknow

Diagnosis and Clinical Approach to Primary Hyperparathyroidism

Dr. Arjun Raja

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Diagnosis and Clinical Approach to Primary Hyperparathyroidism

About the Course

Primary hyperthyroidism is a condition where the parathyroid gland, located in the neck, overproduces parathormone, leading to hypercalcemia due to excessive bone resorption. This excess of hormones accelerates bone resorption, resulting in symptoms such as bone pain, Dyspepsia, Palpitation. The most common cause is Parathyroid Adenoma, an enlargement of parathyroid gland and leading to autonomous production of Parathormone. Other causes include Double adenoma, Parathyroid hyperplasia, Parathyroid carcinoma. Diagnosis typically involves blood tests to measure blood calcium, phosphorous, parathormone levels and imaging studies to assess osteoporosis and end organ damage. Treatment options often include medications to control initial hypercalcemia, followed by definitive management which is surgery in form of parathyroidectomy.