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पाठ्यक्रम के बारे में

•Penicillin is the 1st antibiotic to be discovered

•Bacetricidal due to inhibition of peptigoglycan layer breakdown  in bacterial cell wall

•Resistance due to beta-lactamases, altered PBP & porin channels (Gr –ve)

•Currently these are indicated in some specific indications only because of emergence of resistance

•Safety profile well established except chance of hypersensitivity reactions

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